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  • White jar of Mario Badescu Advanced Peptide PDRN Jelly Cream on a white background
  • Mario Badescu Advanced Peptide PDRN Jelly Cream jar on a light gray background
  • Split image with green leaves on the left and pink liquid with bubbles on the right, featuring '100% Vegan PDRN' text.
  • Person applying Mario Badescu Advanced Peptide PDNR Jelly Cream to their face.
  • Pink cream being squeezed out of a white container on a pink background
  • Pink texture of PDRN Cream
  • Close-up of a hydrated skin patch with 'Triple-Action Hydration' text.
  • Before and after comparison of a woman's face with visible skin improvement.
  • Diagram of micro-sized DNA molecules absorbing into skin on a pink background
  • Woman applying Mario Badescu cream with a applicator on a pink background
  • Mario Badescu PDRN Jelly Cream packaging on a white background
  • Mario Badescu PDRN Jelly Cream jar and packaging on a white background
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Advanced Peptide PDRN Jelly Cream

Advanced Peptide PDRN Jelly Cream

Bounce-back hydration in a lightweight jelly cream. Read More
$16.00
$20.00 $16.00
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Ideal skin type:
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A lightweight, glycerin-rich jelly moisturizer that sinks in quickly to hydrate and deliver a concentrated complex of plant-based PDRN (ultra-refined DNA fragments from plants, developed for efficient absorption and renewal). Niacinamide, Sodium Hyaluronate, and Matrixyl® 3000 peptides—refining texture, targeting the look of fine lines, evening the appearance of tone, and helping strengthen the skin’s moisture barrier. The bouncy jelly glides on and absorbs effortlessly, leaving skin smooth, balanced, and hydrated.

Naturally pink from Vitamin B12; color may vary or fade over time—potency remains intact, and it always applies clear.

#MBSKINTIP: Mix it with our Hydrating Overnight Mask with Peptides to create the ultimate nighttime moisture boost.

Before and after comparison of a woman's face with pink cream, showing skin improvement.

Key Benefits:

  • Helps smooth the look of fine lines
  • Supports skin's natural renewal process
  • Helps calm redness and stressed-looking skin
  • Improves the look of uneven tone
  • Deep hydration with a lightweight feel
  • Helps reinforce the look of the skin barrier
  • Comfortable for daily use

Why is ours different?

  • Salmon-PDRN illustration

    Other Brands

    Use salmon PDRN

  • Hartleaf-PDRN illustration

    Mario Badescu

    Uses plant-derived PDRN

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Our HEARTLEAF-DERIVED VEGAN PDRN uses ULTRA-SMALL DNA fragments that skin can respond to more EFFICIENTLY, with testing showing strong repair signaling, calming, and barrier support.

Also supported by...

  • Close-up of pink bubbles in a liquid

    Matrixyl® 3000

    Peptides to boost collagen production and improve elasticity.

  • Close-up of white cream or gel with a textured surface

    5% Niacinamide

    Strengthens the skin barrier and supports the calming effects of PDRN.

  • Close-up of water droplets on a textured surface with a blue tint.

    Sodium Hyaluronate

    For lasting hydration and plumpness.

  • Pink textured background with small bubbles

    Vitamin B12

    Supports renewal and gives the jelly its natural pink tone.

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Two ways to use

  • Use Solo

    Use it solo after cleansing and serums, pressing or massaging it into the skin. The jelly texture doubles as a glide for facial tools.

  • Super-Charge

    Or boost your routine by mixing a small amount into a water-based moisturizer or serum.

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products to mix with

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Overall rating: 4.880734 / 5 from 109 reviews.

AI Generated Review Summary

This lightweight, whipped-glycerine jelly moisturizer deeply hydrates and rejuvenates the skin, leaving it feeling smooth and plump. Customers appreciate its effectiveness for red and irritated skin, and its ability to strengthen the skin’s barrier.

Summary topics

  • Skin Hydration (40%): A substantial number of customers pointed out that the product leaves their skin feeling hydrated, smooth, and rejuvenated.
  • Effectiveness for Red Skin (25%): Many customers raved about the PDRN Jelly Cream, praising its effectiveness for red/irritated skin.
  • Skin Appearance (20%): A significant number of customers remarked that their skin looks plump, healthy, and hydrated.

Review topics: ["size","results","wrinkles","smells","feels","texture","skin","price","looks","face","lines","use","cream","hydrating","moisturizer","gel","jelly","serum","mario badescu","layer","addition","reaction"].

Review highlights

  • "My skin looks fresher and more hydrated without any stickiness." — Laura
  • "My skin looks plump and healthy!" — Michelle
  • "It makes my face feel so soft and smooth." — Tamika

Reviews

I have been using Mario

"I have been using Mario products since I was 20 (I’m now 40) and swear by this brand. I didn’t do any research about pdrn before trying this, it just looked fun. This is the BEST product, I feel like I look so much younger, it has made my skin smoother and tighter and lightened dark spots and I am getting so many compliments from close friends who see me all the time! I use it after serum in the morning and just on its own before bed. I didn’t take before/after shots but I wish I did. I don’t wear makeup but suddenly my confidence is soaring, I don’t feel like I need it at all."

— Cassi C. (5/5)

Please make a bigger bottle or refill available

"I have now been using this since it came out. It makes such a difference, always. I went through a horrible flu lately, and even though I was re-hydrated body-wise my skin looked amazing as always after this. Try putting it on befoefre the Supper Collagen Mask. I’m not sure if this is recommended, but it worked for me. My only complaint is that I wish it became available in a larger container or refill package. I think the bundle with the metal glider is cool, but I think most of us have one, and this would be much more appreciated."

— megtrouble (5/5)

The PDRN jelly is wonderful.

"The PDRN jelly is wonderful. It’s cooling, goes on easily, and I’ve noticed a difference in my skin’s health. It looks more radiant and youthful. It does feel just slightly tacky after you let it dry before putting on your moisturizer, but that goes away when you add your daily moisturizer or SPF. I have not noticed any reduction in redness, but the overall feel and appearance of my skin has improved. Safe for sensitive skin. I’ve been using it for a few months and would highly recommend."

— Amanda B. (5/5)

Application is smooth and it

"Application is smooth and it does provide a bright and dewy complexion. My only complaint is that you really have to massage the product well into the face or otherwise it feels sticky/tacky on the skin."

— Charlene O. (4/5)

Lots of gel-based products I’ve

"Lots of gel-based products I’ve tried in the past simply disappear on skin —as if they have too much alcohol in them, surprisingly this gel is not heavy, yet it leaves a nice soft dewy layer on skin. I’m currently using it for scar healing and anywhere I feel I need a boost of moisture touchup without heaviness. I’m also extremely pleased with the fact that there’s no bad stuff in here nor fake dyes."

— Debra A. (5/5)

I really enjoy the level

"I really enjoy the level of hydration that I get from this product, and also how little of it I have to use to attain that hydration. This is definitely something that will be a staple in my routine for a very long time to come! In the morning, I put this on after my vitamin C, serum, and in the evening, after my cellufirm drops. It definitely locks everything in and keeps my skin very hydrated. I’m very curious to keep using it to see any additional benefits and to see if it will help with any wrinkles I have in my forehead."

— Tara R. (5/5)

Advanced Peptide PDRN Jelly Cream

"I couple years ago psoriasis appeared on areas of my face. Nothing, including Rx's has helped it go into remission. This jelly cream used with super peptide serum at night and with the vitamin c cream in the morning, has improved areas affected. I'm pretty happy about it!"

— Kathleen M. (5/5)

Calms my facial Eczema 😆

"This Jelly Cream is Amazing. if you have allergy facial eczema. Calms down the dryness & rash that comes with seasonal allergy eczema. Very happy that it's Vegan because of my Many Allergies & one of them is Fish. So soothing I use it with the MB Oil free moisturizer & Repairing Facial Spray with Hypochlorous Acid which is great for itchy eczema rashes. Hope to see more Approved by the National Eczema Association but, even some products on their list I can't use."

— Maria (5/5)

Excellent product

"This is the very first PDRN-related product I have ever used. Overall I am very pleased, and I alternate it with my retinol (I have sensitive skin). However if you have sensitive skin, be mindful of tingling until your skin gets used to it. I had tingling near my eyes the first few uses, but otherwise I love it. You don't even need a lot of product - even a dab is enough to cover 75% of your face."

— Kelley F. (5/5)

I awaken with soft, plump

"I awaken with soft, plump feeling skin. It's only been 10 days, but now I don't wanna skip it at all! I also use the serum underneath."

— Judith B. (5/5)

Q&A

Is the “clinical testing” done on animals?
Mario Badescu does not test products or ingredients on animals, nor do we ask others to test on our behalf.